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Diosmin is a semisynthetic flavonoid molecule derived from citrus d(modified hesperidin).


Diosmin is used for treating various disorders of blood vessels including hemorrhoids, varicose veins, poor circulation in the legs(venous stasis), and bleeding(hemorrhage) in the eye or gums.It is also used to treat swelling of the arms(lymphedema)following breast cancer surgery, and to protect against liver toxicity.It is often taken in combination with hesperidin.


Diosmin is currently a prescription medication, and it also sold as a nutritional supplement.


EP, BP, USP, 90:10, Micronized

Greyish-yellow or light yellow hygroscopic powder.


Citrua aurantium L.



Main Functions and Benefits of Diosmin

Diosmin prolongs the vasoconstrictor effect of norepinephrine on the vein wall, increasing venous tone, and therefore reducing venous capacitance, distensibility, and stasis.

Diosmin increases the venous return and reduces venous hyperpressure present in patients suffering from CVI.

Diosmin improves lymphatic drainage by increasing the frequency and intensity of lymphatic contractions, and by increasing the total number of functional lymphatic capillaries.

Diosmin powder with hesperidine decreases the diameter of lymphatic capillaries and the intralymphatic pressure.

At the microcirculation level, diosmin reduces capillary hyperpermeability and increases capillary resistance by protecting the microcirculation from damaging processes.

Diosmin reduces the expression of endothelial adhesion molecules,and inhibits the adhesion, migration, and activation of leukocytes at the capillary level. Diosmin powder leads to a reduction in the release of inflammatory mediators, principally oxygen free radicals and prostaglandins.

Natural Origin of Hesperidin and Diosmin

Diosmin Against Spider Veins and Varicose Veins



High Assay:≥95% for EP standard

Impurity Control: Total impurities≤4%

Low Pesticide Residue

Diosmin can be used as raw material for medicines in pharmaceutical field.

Diosmin can be used as raw material in health care product and supplement field.

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